SCIENTIFIC PROGRAM

Thursday, November 18th, 2004

17:00-18:00 Registration - (School of Medicine, 1st floor, Salon de Actos)
18:00-18:30 Opening Ceremony
18:00-19:00 Opening Lecture
Chairman: F. Casanueva (Spain), C. Dieguez (Spain), M. Pombo (Spain)
A century of growth hormone research revisited - from linear models to network complexity
C. Kordon (France)
19.30 Welcome Cocktail - (Hotel Reyes Catolicos)

Friday, November 19th, 2004

- SESSION I -
Basic Concepts On Ghrelin Regulation And Action

Chairman: J. P. Castano (Spain) and G. Cuatrecasas (Spain)

09:00-09:30 Background and hypothalamic regulation
S. L. Dickson (Sweden)
09:30-10:00 Endocrine and cardiovascular actions
E. Ghigo (Italy)
10:00-10:30 The neuroendocrinology of "diabesity": Perspectives for drug hunting.
M. Tschoep (USA-Germany)
10:30-11:00 Regulation of gonadal function
M. Tena-Sempere (Spain)
11:00-11:30 Coffee-break

- SESSION II -
Growth Hormone

Chairman: A. Spada (Italy) and B. Bonet (Spain)

11:30-12:00 Origin and fate of the GH cell network
P. Mollard (France)
12:00-12:30 Regulation of the somatotrope axis
I. C. A. F. Robinson (UK)
12:30-13:00 The biological meaning of GH pulsatility
A. Barkan (USA)
13:00-13:30 Assessment by microarrays of GH biological action
G. Norstedt (Sweden)
13:30-15:30 Lunch - (Hotel Reyes Catolicos)

- SESSION III -
GH Deficiency

Chairman: A. Ferrandez (Spain) and M. Mascarenhas (Spain)

15:30-16:00 Genetic basis of short stature
L. Castro (Spain)
16:00-16:30 Intrauterine growth retardation
A. C. S. Hokken-Koelega (Holland)
16:30-17:00 Radiation-induced hypopituitarism"
S. Shalet (UK)
17:00-17:30 Metabolic consequences of GH deficiency
J.O. Jørgensen (Denmark)
17:30-18:30 POSTER SESSION & coffee-break

Saturday, November 20th, 2004

- SESSION IV -
GH Excess

Chairman: S. Webb (Spain) and TBC

09:00-09:30 Diagnostic and therapeutic consensus of acromegaly
A. Giustina (Italy)
09:30-10:00 The outcome of surgery and radiotherapy, the endocrinologist view
D. Kleinberg (USA)
10:00-10:30 Severe systemic complications of acromegaly
A. Colao (Italy)
10:30-11:00 The critical parameters in GH excess
M. Sheppard (UK)
11:00-11:30 Coffee-break

- SESSION V -
The role of IGF

Chairman: J. P. Lopez- Siguero (Spain) and P. Martul (Spain)

11:30-12:00 Biological actions of liver-derived IGF-I
D. Le Roith (USA)
12:00-12:30 The IGF-1 system in children
J. Argente (Spain)
12:30-13:00 The debated relationship IGF-I - cancer
J. Wass (UK)
13:00-13:30 The genetic control of IGF-I levels and its consequences
S. W. J. Lamberts (The Netherlands)
13:30-15:30 Lunch¡ - (Hotel Reyes Catolicos)

- SESSION VI -
New Agents And New Indications

Chairman: A. Leal (Spain) and R. Blizzard (USA)

15:30-16:00 Hypopituitarism as a consequence of traumatic brain injury - call for attention
V. Popovic (Serbia-Montenegro)
16:00-16:30 Indications for GH replacement in adolescents and young adults
J. P. Monson (UK)
16:30-17:00 Deficiency of the IGF system associated with inactivation of the ASL gene
H. M. Domené (Argentina)
17:00-17:30 From cell biology to clinic. New therapeutic strategies
P. H. Jacquet (France)
17:30- 17:45 Closing Remarks
R. Blizzard (USA)

Venue
The conference will take place at the: Faculty of Medicine of Santiago de Compostela
C/ Rùa de San Francisco s/n 15782 Santiago De Compostela Spain

Language
The official language of this conference will be English

Mutual Recognition of CME credits
There is an official agreement for mutual recognition of CME credits between the European Accreditation Council for
Continuing Medical Education (EACCME) and the American Medical Association (AMA).

Registration
The registration fee is € 325 before September 15th, 2004 and € 400 after this date.
Students, paramedical staff and trainees registration fee is: € 250 before September 15th, 2004 and € 325 after this date.
Note: for students, paramedical staff and trainees, a letter certifying status must accompany registration.
* If you require special assistance (wheelchair, auxiliary aids) or special dietary requirements, please indicate and we will contact you.

Hotel Accommodation
See the enclosed Hotel Accommodation Form

Travel Information
How to reach Santiago de Compostela:
By plane: Aeropuerto de Lavacolla (Ctra. Santiago-Lugo Km. 11, Lavacolla)
By train: Renfe Station (Rúa do Hórreo, Santiago de Compostela).
Trains daily to Madrid, Bilbao, La Coruña, Vigo and Orense.
Connections to Portugal and France.